- Saad, Brandon
- Saavedra, Miguel
- Sabathia, C.C.
- Sabatini, Fabio
- Sabatini, Gabriela
- Sabbatini, Rory
- Sabonis, Arvydas
- Sacco, Joe
- Sacks, Greg
- Sadler, Donnie
- Sadler, Elliott
- Sadler, Hermie
- Sadler, Richard
- Saenz, Olmedo
- Safarova, Lucie
- Saffold, Rodger
- Safin, Marat
- Sagan, Peter
- Said, Boris
- Saine, Brandon
- Saito, Takashi
- Sakic, Joe
- Salak, Alexander
- Salas, Greg
- Salazar, Roger
- Sale, Chris
- Salei, Ruslan
- Sales, Nykesha
- Salley, John
- Salmon, Tim
- Salmons, John
- Salo, Sami
- Salo, Tommy
- Saltalamacchia, Jarrod
- Salvador, Bryce
- Samardzija, Jeff
- Sampras, Pete
- Sampson, DeMarco
- Samson, Jerome
- Samsonov, Sergei
- Samuel, Asante
- Samuel, Khari
- Samuels, Chris
- Samuels, Samardo
- Samuelsson, Mikael
- Sanches, Brian
- Sanchez, Angel
- Sanchez, Anibal
- Sanchez, Frank
- Sanchez, Freddy
- Sanchez, Gaby
- Sanchez, Javier
- Sanchez, Jesus
- Sanchez, Jonathan
- Sanchez, Mark
- Sanchez, Rey
- Sandberg, Ryne
- Sanders, Bob
- Sanders, Chris
- Sanders, Deion
- Sanders, Doug
- Sanders, Emmanuel
- Sanders, Frank
- Sanders, James
- Sanders, Jeff
- Sanders, Larry
- Sanders, Lewis
- Sanders, Reggie
- Sanders, Sara
- Sanderson, Geoff
- Sandoval, Pablo
- Sands, Mike
- Sands, Robert
- Sanford, Curtis
- Sanford, Jamarca
- Santana, Carlos
- Santana, Ervin
- Santana, Johan
- Santana, Manuel
- Santiago, Benito
- Santiago, Daniel
- Santiago, Jose
- Santiago, Ramon
- Santo, Ron
- Santorelli, Mike
- Santos, Bobby
- Santos, Sergio
- Sanzenbacher, Dane
- Sapp, Benny
- Sapp, Warren
- Saprykin, Oleg
- Sarich, Cory
- Sasaki, Kazuhiro
- Sash, Tyler
- Satan, Miroslav
- Satele, Samson
- Saturday, Jeff
- Sauerbeck, Scott
- Sauerbrun, Todd
- Sauerbrunn, Becky
- Saunders, De'Ante
- Saunders, Flip
- Saunders, Joe
- Saunders, Michael
- Saunders, Weslye
- Sauter, Cory
- Sauter, Johnny
- Savage, Brian
- Savard, David
- Savard, Marc
- Sayers, Gale
- Sbisa, Luca
- Scalabrine, Brian
- Scandella, Marco
- Scandrick, Orlando
- Scarallo, Joey
- Scarponi, Michele
- Scatchard, Dave
- Schaefering, Brian
- Schalk, Ray
- Schaub, Matt
- Scheepers, Chanelle
- Scheffler, Tony
- Schendel, Tim
- Schenn, Brayden
- Scherrer, Tom
- Scherzer, Max
- Schiavone, Francesca
- Schierholtz, Nate
- Schilens, Chaz
- Schilling, Curt
- Schilling, Stephen
- Schlauderaff, Caleb
- Schleck, Andy
- Schleck, Frank
- Schlereth, Daniel
- Schlesinger, Cory
- Schlitter, Brian
- Schmidt, Jason
- Schmidt, Joe
- Schmidt, Mike
- Schmitt, Owen
- Schneider, Brian
- Schneider, Cory
- Schneider, Larry
- Schneider, Mathieu
- Schnellenberger, Howard
- Schnyder, Patty
- Schoendienst, Red
- Schoenweis, Scott
- Schrader, Ken
- Schrempf, Detlef
- Schroeder, Bill
- Schroeder, John
- Schroeder, Ted
- Schuettler, Rainer
- Schuller, Rick
- Schulters, Lance
- Schultz, Jeff
- Schultz, Nick
- Schultz, Ray
- Schultz, Scott
- Schulz, Kurt
- Schulz, Ted
- Schumaker, Skip
- Schwank, Eduardo
- Schwartz, Geoff
- Schwartz, Jim
- Schwartzel, Charl
- Scifres, Mike
- Scioscia, Mike
- Scobee, Josh
- Scola, Luis
- Scott, Adam
- Scott, Bart
- Scott, Bernard
- Scott, Brian
- Scott, Byron
- Scott, Chad
- Scott, Chris
- Scott, Da'Rel
- Scott, Darell
- Scott, Darnay
- Scott, Gina
- Scott, Jake
- Scott, John
- Scott, Jonathan
- Scott, Luke
- Scott, Lynn
- Scott, Sean
- Scott, Steve
- Scott, Travis
- Scott, Trevor
- Scroggins, Tracy
- Scuderi, Rob
- Scutaro, Marco
- Seabrook, Brent
- Searcy, Da'Norris
- Searcy, Leon
- Seau, Junior
- Seaver, Tom
- Seder, Tim
- Sedin, Daniel
- Sedin, Henrik
- Sefolosha, Thabo
- Segares, Gonzalo
- Segui, David
- Seguin, Tyler
- Sehorn, Jason
- Seidenberg, Dennis
- Seiple, Larry
- Sela, Dudi
- Selanne, Teemu
- Selby, Josh
- Sele, Aaron
- Selee, Frank
- Seles, Monica
- Sellers, Mike
- Sellers, Peyton
- Selmon, Lee Roy
- Semenya, Caster
- Semin, Alexander
- Sendejo, Andrew
- Senden, John
- Senna, Ayrton
- Sensabaugh, Gerald
- Seppi, Andreas
- Sepulveda, Daniel
- Seraphin, Kevin
- Serra, Florent
- Serrano, Antonio
- Servais, Scott
- Session, Clint
- Sessions, Ramon
- Setoguchi, Devin
- Setzer, Dennis
- Seubert, Rich
- Sevastova, Anastasija
- Sewell, Joe
- Sexon, Richie
- Seymour, Richard
- Shade, Sam
- Shanahan, Brendan
- Shanahan, Mike
- Shanle, Scott
- Shannon, Randy
- Sharapova, Maria
- Sharp, Patrick
- Sharpe, Shannon
- Sharper, Darren
- Sharper, Jamie
- Shattenkirk, Kevin
- Shaughnessy, Matt
- Shaver, Tony
- Shaw, Andrew
- Shaw, Billy
- Shaw, Bobby
- Shaw, Brian
- Shaw, Jeff
- Shaw, Terrance
- Shaw, Tom
- Shea, Aaron
- Sheard, Jabaal
- Sheehan, Patty
- Sheets, Andy
- Sheets, Ben
- Sheffield, Gary
- Sheldon, Mike
- Shell, Art
- Shelley, Jody
- Shelton, Daimon
- Sheltra, Patrick
- Shen Xue
- Shepard, Linda
- Shepherd, Morgan
- Sherels, Marcus
- Sherfy, Brad
- Sherman, Richard
- Sherrill, George
- Sherrod, Derek
- Shiancoe, Visanthe
- Shields, James
- Shields, Paul
- Shields, Sam
- Shields, Scot
- Shields, Steve
- Shields, Will
- Shipley, Jordan
- Shipp, Marcel
- Shirley, Jason
- Shockey, Jeremy
- Shoppach, Kelly
- Short, Brandon
- Shorts, Cecil
- Showalter, Buck
- Shula, Don
- Shuler, Mickey
- Shumpert, Iman
- Shuster, John
- Shvedova, Yaroslava
- Sidbury, Lawrence
- Sidney, Dainon
- Siedlecki, Jack
- Sieg, Ryan
- Sieg, Shane
- Sierra, Ruben
- Sifford, Charlie
- Sigel, Jay
- Silas, Paul
- Siler, Brandon
- Sillinger, Mike
- Silva, Mana
- Silva, Ricardo
- Simmonds, Wayne
- Simmons, Al
- Simmons, Anthony
- Simmons, Bobby
- Simmons, Brian
- Simmons, Cedric
- Simmons, Clyde
- Simmons, Jason
- Simmons, Tony
- Simon, Alfredo
- Simon, Chris
- Simon, Corey
- Simon, Gilles
- Simon, Randall
- Simoneau, Mark
- Simpson, Jerome
- Simpson, Mark
- Simpson, O.J.
- Simpson, Scott
- Simpson, Todd
- Simpson, Webb
- Sims, Barry
- Sims, David
- Sims, Ernie
- Sims, Eugene
- Sims, Rob
- Sims-Walker, Mike
- Sinceno, Kaseem
- Sinclair, Michael
- Sindelar, Joey
- Singh, Vijay
- Singler, Kyle
- Singletary, Mike
- Singleton, Chris
- Singleton, Chris, (basketball)
- Sipp, Tony
- Siragusa, Tony
- Sirmon, Peter
- Sisco, Andrew
- Sisler, George
- Sitton, Josh
- Sizemore, Grady
- Skelton, John
- Skiles, Scott
- Skille, Jack
- Skinner, Brian
- Skinner, Jeff
- Skinner, Mike
- Skrastins, Karlis
- Skrine, Buster
- Skuta, Dan
- Slade, Chris
- Slaten, Doug
- Slater, Jackie
- Slater, Kelly
- Slaton, Steve
- Slaughter, Chad
- Slaughter, Enos
- Slauson, Matt
- Sloan, David
- Sloan, Tyler
- Slocum, Heath
- Slowey, Kevin
- Sluman, Jeff
- Smaby, Matt
- Small, Mike
- Small, Torrance
- Smart, Keith
- Smith, Aaron
- Smith, Akili
- Smith, Aldon
- Smith, Alex
- Smith, Alfonso
- Smith, Alphonso
- Smith, Andre
- Smith, Anthony
- Smith, Antone
- Smith, Antonio
- Smith, Antowain
- Smith, Armond
- Smith, Ben, (football)
- Smith, Ben, (ice hockey)
- Smith, Brad
- Smith, Brady
- Smith, Brandon
- Smith, Brendan
- Smith, Brian
- Smith, Bruce
- Smith, Chris
- Smith, Chuck
- Smith, Courtney
- Smith, Craig
- Smith, D.J.
- Smith, Darrin
- Smith, Daryl
- Smith, Dave
- Smith, David
- Smith, Derek
- Smith, Derrell
- Smith, Dick
- Smith, Emmitt
- Smith, Eric
- Smith, Fernando
- Smith, Frankie
- Smith, Greg
- Smith, Herb
- Smith, Hilton
- Smith, Hunter
- Smith, Ish
- Smith, J.R.
- Smith, Jackie
- Smith, Jason (football)
- Smith, Jason, (basketball)
- Smith, Jason, (football)
- Smith, Jeff
- Smith, Jeremy
- Smith, Jim
- Smith, Jimmy, (football)
- Smith, Jimmy, (mixed martial arts)
- Smith, Joe, (baseball)
- Smith, Joe, (basketball)
- Smith, Josh
- Smith, Justin
- Smith, Kevin
- Smith, Lamar
- Smith, LaQuentin
- Smith, Larry
- Smith, Lee
- Smith, Lovie
- Smith, Malcolm
- Smith, Marcus
- Smith, Marquis
- Smith, Marvel
- Smith, Maurice
- Smith, Mike, (football coach)
- Smith, Mike, (hockey)
- Smith, Nolan
- Smith, Omar
- Smith, Otis
- Smith, Regan
- Smith, Reggie
- Smith, Robaire
- Smith, Roscoe
- Smith, Roy
- Smith, Rusty
- Smith, Sally
- Smith, Sean
- Smith, Seth, (baseball)
- Smith, Shaun
- Smith, Steve
- Smith, Steve
- Smith, Steve
- Smith, Taj
- Smith, Taylor
- Smith, Terrelle
- Smith, Thomas
- Smith, Tom
- Smith, Torrey
- Smith, Troy
- Smith, Tyron
- Smith, Wade
- Smith, Walter
- Smith, Will
- Smith, Wyatt
- Smoak, Justin
- Smolinski, Bryan
- Smyth, Ryan
- Snead, J.C.
- Snedeker, Brandt
- Snee, Chris
- Snelling, Jason
- Snider, Duke
- Snider, Travis
- Snow, Eric
- Snow, Garth
- Snow, Justin
- Snyder, Chris
- Snyder, Dan
- Snyder, Joey
- Snyder, John
- Snyder, Patty
- So'oto, Vic
- Sobotka, Vladimir
- Soderling, Robin
- Sogard, Eric
- Sojo, Luis
- Solder, Nate
- Soliai, Paul
- Solo, Hope
- Solomon, Beth
- Sonnanstine, Andy
- Sopel, Brent
- Sorensen, Chris Anker
- Sorensen, Nick
- Sorensen, Nicki
- Sorenson, Reed
- Sorenstam, Annika
- Soria, Joakim
- Soriano, Alfonso
- Soriano, Rafael
- Sosa, Sammy
- Soto, Geovany
- Soumare, Bakary
- Souray, Sheldon
- Sousa, Kevin
- Sowards, Bob
- Sowell, Jerald
- Spacek, Jaroslav
- Spach, Stephen
- Spaeth, Matt
- Spagnuolo, Steve
- Spahn, Warren
- Spaling, Nick
- Span, Denard
- Sparano, Tony
- Sparks, Phillippi
- Sparks, Steve
- Speaker, Tris
- Spears, Marcus
- Spears, Quinton
- Speights, Marreese
- Spencer, Anthony
- Spencer, Chris
- Spencer, Jimmy
- Spencer, John
- Spencer, Marcus
- Spencer, Owen
- Spencer, Shane
- Spencer, Shawntae
- Speraw, Kirk
- Spicer, Paul
- Spievey, Amari
- Spiezio, Scott
- Spikes, Brandon
- Spikes, Cameron
- Spikes, Takeo
- Spilborghs, Ryan
- Spillane, Johnny
- Spiller, C.J.
- Spires, Greg
- Spitz, Jason
- Spivey, Junior
- Splitter, Tiago
- Spoelstra, Erik
- Sprague, Ed
- Sprewell, Latrell
- Spriggs, Marcus
- Springer, George
- Springer, Mike
- Springs, Shawn
- Sproles, Darren
- Spurgeon, Jared
- Staal, Eric
- Staal, Jordan
- Staal, Marc
- Stack, Mike
- Stackhouse, Jerry
- Stadler, Craig
- Stafford, Drew
- Stafford, Matthew
- Staios, Steve
- Stairs, Matt
- Stakhovsky, Sergiy
- Stalberg, Viktor
- Staley, Duce
- Staley, Joe
- Stallworth, Donte
- Stambaugh, Phil
- Stamkos, Steven
- Standeford, John
- Stankowski, Paul
- Stanley, Chad
- Stanton, Drew
- Stanton, Mike
- Stanton, Mike (Florida Marlins)
- Stanzi, Ricky
- Starace, Potito
- Stargell, Willie
- Starks, Duane
- Starks, James
- Starks, John
- Starks, Randy
- Starling, Bubba
- Starr, Bart
- Starr, David
- Stastny, Paul
- Staubach, Roger
- Staubitz, Brad
- Stauffer, Tim
- Stecker, Aaron
- Steen, Alex
- Stein, Blake
- Steinberg, Jeff
- Steinbrenner, Hank
- Steiner, Mike
- Steinhauer, Sherri
- Steltz, Craig
- Stemke, Kevin
- Stempniak, Lee
- Stenerud, Jan
- Stengel, Casey
- Stenhouse, Ricky, Jr.
- Stenson, Henrik
- Stepan, Derek
- Stepanek, Radek
- Stepania, Vladimir
- Stephens, Jamain
- Stephens, Reggie
- Stephens, Sloane
- Stephens-Howling, LaRod
- Stephenson, Dwight
- Stephenson, Jan
- Stephenson, Lance
- Stetter, Mitch
- Steussie, Todd
- Stevens, Craig
- Stevens, Kevin
- Stevens, Lee
- Stevens, Matt
- Stevens, Scott
- Stevenson, Alexandra
- Stevenson, Deshawn
- Stevenson, Eric
- Stevenson, Jeremy
- Stewart, Chris
- Stewart, Chris, (football)
- Stewart, Darian
- Stewart, Ian
- Stewart, Jeff
- Stewart, Jonathan
- Stewart, Kordell
- Stewart, Matt
- Stewart, Michael
- Stewart, Ray
- Stewart, Rayna
- Stewart, Russell
- Stewart, Scott
- Stewart, Shannon
- Stewart, Tony
- Stiemsma, Greg
- Still, Mike
- Stillman, Cory
- Stills, Gary
- Stinnett, Kelly
- Stith, Bryant
- Stith, Shyrone
- Stitser, Clint
- Stocker, Luke
- Stockton, Dave
- Stockton, John
- Stoerner, Clint
- Stoitchkov, Hristo
- Stojakovic, Peja
- Stokley, Brandon
- Stoll, Jarret
- Stolle, Fred
- Stone, John
- Stone, Ron
- Stoner, Clayton
- Storen, Drew
- Storr, Jamie
- Stosur, Samantha
- Stoudamire, Damon
- Stoudemire, Amare
- Stovall, Maurice
- Stover, Matt
- Strahan, Michael
- Straka, Martin
- Stralman, Anton
- Strange, Curtis
- Strasburg, Stephen
- Straub, Tim
- Strawberry, Darryl
- Street, Huston
- Streets, Tai
- Stricker, Steve
- Strickland, Donald
- Strickland, Gary
- Strickland, Rod
- Strickland, Scott
- Strief, Zach
- Stringer, Korey
- Strong, Ken
- Strong, Mack
- Strop, Pedro
- Strother, Ann
- Stroughter, Sammie
- Strudwick, Jason
- Stuart, Brad
- Stubblefield, Dana
- Stubbs, Drew
- Stuckey, Chansi
- Stuckey, Darrell
- Stuckey, Rodney
- Studebaker, Andy
- Stupples, Karen
- Sturdivant, Quan
- Sturm, Marco
- Sturtze, Tanyon
- Stydahar, Joe
- Stynes, Chris
- Subban, P.K.
- Succop, Ryan
- Suggs, Terrell
- Suh, Ndamukong
- Suisham, Shaun
- Sullinger, Jared
- Sullivan, Chip
- Sullivan, Chris
- Sullivan, John
- Sullivan, Mike
- Sullivan, Scott
- Sullivan, Steve
- Sullivan, Tom
- Sulzer, Alexander
- Summerhays, Bruce
- Summers, DaJuan
- Sundhage, Pia
- Sundin, Mats
- Sung, Park Ji
- Sunsing, William
- Suppan, Jeff
- Sura, Bob
- Surhoff, B.J.
- Surtain, Patrick
- Suter, Gary
- Suter, Ryan
- Sutherland, David
- Sutherland, Kevin
- Sutherland, Vinny
- Sutter, Brandon
- Sutter, Ron
- Sutton, Andy
- Sutton, Don
- Sutton, Hal
- Sutton, Mandy
- Sutton, Tyrell
- Suzuki, Ichiro
- Suzuki, Kurt
- Suzuki, Mac
- Sveum, Dale
- Svitek, Will
- Svoboda, Petr
- Swain, Brett
- Swann, Lynn
- Swanson, Brian
- Swanson, Matt
- Swayne, Harry
- Sweeney, Matt
- Sweeney, Mike
- Sweeney, Ryan
- Sweet, Brad
- Swift, Justin
- Swift, Stromile
- Swindell, Greg
- Swindell, Kevin
- Swisher, Nick
- Sydor, Darryl
- Sykora, Petr
- Sylvester, Austin
- Sylvester, Stevenson
- Szavay, Agnes
- Szczechura, Paul
- Szczerbiak, Wally